Immune privileged sites, such as the brain, the eye, and the testis, are often the targets of autoimmune attack. Thus, once effector T cells are generated that have specificity for autoantigens expressed in these tissues, the effector cells can gain entry to the tissue and cause tissue damage. However, under normal circumstances, the priming and differentiation of effector cells specific for antigens found in the brain, for example, is generally prevented. This is because 'immune privileged' sites:

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Biology

Ruffe

Yesterday, 05:43

Immune privileged sites, such as the brain, the eye, and the testis, are often the targets of autoimmune attack. Thus, once effector T cells are generated that have specificity for autoantigens expressed in these tissues, the effector cells can gain entry to the tissue and cause tissue damage. However, under normal circumstances, the priming and differentiation of effector cells specific for antigens found in the brain, for example, is generally prevented. This is because 'immune privileged' sites:

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Jan Padilla · Answer 1

express the cytokine, TGF-beta

Explanation:

An autoimmune disease is a condition in which your immune system attacks your body mistakenly. The immune system protects our body against germs including bacteria and viruses. It sends out an army of fighter cells to attack them.

Immune privileged sites, such as the brain, the eye, and the testis, are often the targets of autoimmune attack but the priming and differentiation of effector cells specific for antigens found in the brain, for example, is generally prevented as immune-privileged sites express the cytokine, TGF-beta.