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6 May, 10:14

Cystic fibrosis is caused by the allele f, which is completely recessive to the normal dominant allele F. Consider a couple with the genotype Ff. What is the chance that their first child will develop cystic fibrosis?

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  1. 6 May, 10:36
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    Explanation:

    Given that the disease cystic fibrosis is caused by a recessive allele (f), the individuals with genotype "ff" will express the disease. Both "FF and Ff" genotype will give the individuals a normal phenotype.

    Both the parents are carrier (Ff) for the disease. They have 3/4 probability of getting a healthy child and 1/4 probability of getting a child with cystic fibrosis.
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