Which statement is NOT part of the Mitchell chemiosmotic hypothesis? High‑energy phosphorylated intermediates that serve as phosphate donors to ADP are generated as a result of electron‑transfer reactions. The use of electron transfer to provide the energy for ATP synthesis requires an intact membrane. A portion of the energy from electron transport is used to generate a proton‑motive force, which provides the energy for ATP synthesis. ATP production is driven by the formation of a proton gradient between the matrix (low proton concentration) and the intermembrane space (high proton concentration).

High-energy phosphorylated intermediates that serve as phosphate donors to ADP are generated as a result of electron-transfer reactions.

Explanation:

Peter Mitchell proposed Chemiosmotic hypothesis which state that the driving of the synthesis of ATP is accomplished by a proton-motive force. He propose that whenever electron is moved along the electron transfer chain then proton will be moved accross the inner part of mitochondria membrane. As a result of this there would be increase in PH of the mitochondria matrix and reduced PH of the intermembrane space.

Some Evidence about Chemiosmotic hypothesis hypothesis;

1) transportation of electron brings about the generatation of a proton gradient. there is difference in the PH on the outside and inside the mitochondria.

2) To synthesis ATP, a proton gradient is required only and other means by which PH gradient is generated

Therefore, High-energy phosphorylated intermediates that serve as phosphate donors to ADP are generated as a result of electron-transfer reactions is not Micheal Mitchell statement.