How does a disturbance in the ability to synthesize collagen affect the body?

The disturbance in the ability to synthesize collagen causes several effects like ageing, causes wrinkles, muscular and joint stiffness, frequent fatigue, lack of tonus etc.

Collagen is one of the major fibres found in the connective tissue with its functions of cohesion between organs and tissues and providing elasticity, and flexibility properties.

With decrease in collagen protein reduction of function, loss of elasticity and flexibility occurs.