Which of the following is characteristics of a steroid hormone action?

internal receptor binding

second messenger activation

protein phosphorylation

cell-surface receptor binding

exchanger of GDP with GTP

internal receptor binding

Explanation:

This is because steroid hormones are lipids by nature (usually composed of cholesterol) so they are hydrophobic. This means that steroid hormones can easy pass through the membrane and bind to their internal receptors.

Internal receptors also known as intracellular receptors have DNA binding domain and when hormones bind to them DNA-binding site becomes exposed. Hormone-receptor complex gets into the nucleus and binds to regulatory regions of the DNA. Cellular response is gene expression.