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9 March, 06:58

Which of the following best describes the significance of the TATA box in eukaryoticpromoters? A) It is the recognition site for a specific transcription factor. B) It sets the reading frame of the mRNA. C) It prevents supercoiling of the DNA near the start site. D) It is the recognition site for ribosomal binding. E) Its significance has not yet been determined.

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  1. 9 March, 09:57
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    A) It is the recognition site for a specific transcription factor

    Explanation:

    Promoter is non-coding DNA sequence responsible for initiation of transcription, as a first and most import step in the regulation of gene expression. Usually changing of promoter nucleotide sequence can lead to loss of promoter function.

    In eukaryotic cell, promoter is associated with with other regulatory regions such as enhancers, silencers, insulators. The structure of eukaryotic promoter includes the binding site for the enzyme RNA polymerase, site for the binding of regulation factors (such as TATA box), the transcription start site.
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