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30 July, 19:11

With the assumption that schmid-type metaphyseal chondrodysplasia is rare, is this type of dwarfism inherited as a dominant or recessive trait and why?

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  1. 30 July, 20:07
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    Answer and explanation;

    -The nearly one-to-one ratio seen in the offspring suggests it is likely inherited as a dominant trait, with the dwarf parent being heterozygous for the dwarf allele along with the normal parent being homozygous for the normal allele.

    -Metaphyseal chondrodysplasia, Schmid type (MCDS) is a type of skeletal disorder in which there is abnormal bone formation at the end of the long bones (metaphyses). MCDS is caused by a mutation in one of the collagen genes. The MCDS mutation is passed on in an autosomal dominant manner.
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