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14 January, 17:23

Prior to administering a dose of 5-FU to a patient with pancreatic cancer, the nurse is conducting the necessary drug research. The nurse is aware that 5-FU is a cell cycle-specific chemotherapeutic agent. Which statement best describes cell cycle-specific drugs?

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  1. 14 January, 18:25
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    They affect cancerous cells during a particular phase of cellular reproduction.

    Explanation:

    Cell cycle-specific drugs are chemotherapy drugs including cancer, they kill cancer when the cancer cells when they're dividing or active, unlike cell cycle non specific that kills cancer when cells when at rest mode.

    Usually considered to be the most effective against tumor in cancer patients.

    For example, the following are some of the antitumor antibiotics are:

    Anthracyclines: Mitoxantrone and Idarubicin.

    Chromomycins: Dactinomycin and Plicamycin.

    Miscellaneous: Mitomycin and Bleomycin
  2. 14 January, 18:52
    0
    The statement that best describes cell cycle-specific drugs is that cell cycle-specific drugs acts by affecting cells during cellular reproduction, the cells they affects are not normal cells but cancerous cells and This occurs/happens during a particular/specific phase of cellular reproduction.

    Rapid cycling ensures that the cell passes through the phase in which it is vulnerable to the drugs' effects.

    These drugs also act during multiple phases of cell cycle and are thus considered as cell cycle specific.

    Examples of cell cycle-specific drugs are; Anthracyclines: Doxorubicin, Daunorubicin, Epirubicin, Mitoxantrone, and Idarubicin. Chromomycins: Dactinomycin and Plicamycin.
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