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22 October, 13:39

Wich phase of the cell cycle is most affected by cytarabine

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  1. 22 October, 17:19
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    Its mode of action is due to its rapid conversion into cytosine arabinoside triphosphate, which damages DNA when the cell cycle holds in the S phase (synthesis of DNA). Rapidly dividing cells, which require DNA replication for mitosis, are therefore most affected.
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