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10 February, 01:24

Which term describes the stage at which cohesins disappear and allow the centromeres to move apart in animal cells?

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  1. 10 February, 02:48
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    Anaphase

    Explanation:

    Anaphase includes two major events:

    Separation of sister chromatids-is due to the destruction of cohesin protein which is catalysed by separase enzyme

    Prior to anaphase securin binds to separase and inhibits its activity

    The APC with specificity factor cdc 20 targets securin for polyubiquitination which then degraded by proteasome

    The released separase becomes active and then breaks the cross link (bridge) between sister chromatids

    Movement of sister chromatids-occurs towards their respective poles due to shortening of kinetochore microtubules
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