What organism is the wolf's life intertwined with?

Humans

Explanation:

Humans are multicellular organisms which have an intertwine relationship with wolves from time immemorial.

Wolves are known to be very intelligent animals and may have followed people who specialized in order to gain access to the remains of carcasses that the hunters couldn't use.

They are able to bond well with humans and identified humans as part of its social pack. Wolves have undergone some form of transformation in recent years to become Dogs which still exhibits all the features of the wolves.