What are the major mechanisms of epigenetic genome modification?

Select the five correct answers.

Select the five correct answers.

DNA acetylation

histone modification involving acetyl, methyl, and phosphate groups

DNA remodeling

chromatin-modifying enzymes methylation

histone modification involving acetyl, amino, and methoxy groups

chromatin remodeling

DNA methylation

binding of long noncoding RNAs to target mRNA molecules

binding of RISC to target mRNA molecules

long noncoding RNAs binding to chromatin-modifying enzymes

1) DNA methylation

2) Chromatin remodeling

3) Long noncoding RNAs binding to chromatin-modifying enzymes

4) Histone modification involving acetyl, methyl, and phosphate groups

5) DNA acetylation

Explanation:

Epigenetic modifications are stable and inherited alterations in the expression of gene and cellular function that does not affect the DNA sequence.

DNA methylation long non coding RNAs binding to chromatin modifying enzymes Binding of RISC to target mRNA molecules histone modification involving acetyl, methyl and phosphate group chromatin remodeling

Explanation:

Epigenetic modifications may alter DNA accessibility and chromatin structure, thereby regulating pattern of gene expression. This safeguards the maintenance of cell identity. The term "epigenetics" refers to the study of the heritable phenotype changes in gene expression that occur without changing the primary DNA sequence. Examples of mechanism that produce such changes are: DNA methylatione and histone modification, where gene expression are altered without altering underlying DNA sequence.