To learn more about Griffith's experiment, scientists extracted a mixture of

various molecules from the heat-killed bacteria. They found that transformation

I translation / transcription) no longer occurred when they treated the mixture

with enzymes that destroyed (lipids / proteins / DNA/RNA / carbohydrates).

This experiment supports the hypothesis that (lipids / proteins / DNA/RNA /

carbohydrates) is the genetic material.

To learn more about Griffith's experiment, scientists extracted a mixture of various molecules from the heat-killed bacteria. They found that transformation no longer occurred when they treated the mixture with enzymes that destroyed DNA/RNA. This experiment supports the hypothesis that DNA/RNA is the genetic material.

Explanation:

Frederick Griffith, a bacteriologist, performed a series of experiments using Streptococcus pneumoniae and mice as a model for his study because he wanted to develop a vaccine against pneumonia. In his experiments, he used R strain bacteria (non-virulent) and S strain bacteria (virulent).

Griffith observed that, when combining the two strains, not only the virulent bacteria killed the mice but the non-virulent bacteria did as well. So, he stated that there was a "transforming principle" that converted non-virulent bacteria into virulent.

Then, Avery and colleagues observed that using enzymes that degrade the DNA remove the transforming activity. However, they didn't believe it was DNA that caused this, but proteins.

Later on, Hershey and Chase discovered that this "transforming principle" was DNA / RNA and was the genetic material that transferred this 'virulence', not proteins as they had concluded before.