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18 March, 19:18

Based on your phylogenetic tree, how many times-at a minimum-do you infer that an HIV virus has jumped hosts to humans?

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  1. 18 March, 20:33
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    Phylogeny and virus

    Explanation:

    Human immune deficiency virus forms the major cause of AIDS (Acquired immune deficiency syndrome)

    Phylogenetic analyses have showed that chimpanzees were the original hosts for this class of viruses Four lineages of HIV have arisen due to the independent cross species transmission to humans and two of these transmissions may have been through gorillas Simian immunodeficiency viruses (SIV) are the closest relatives of HIV infecting wild type chimpanzees and gorillas in west central Africa 98% of HIV infections are caused by HIV-1 group M, the virus has a fast rate of evolution and must have circulated within the population of humans for many years First species found to be infected naturally were African green monkeys where prevalence of infection is high HIV-1 and HIV-2 form a distinct clade within the lentiviruses indicating that humans have acquired their infections from other primates Sooty mangabeys (monkey) in West Africa ere the source of HIV-2 strains and there must have been multiple mangabey to human cross species jump A virus related to HIV-1 was reported in the year 1989 and was found in two captive chimpanzees in Gabon In 1999 a example of SIV was found from a chimpanzee Transmission from chimpanzee to humans gave rise to M and N groups which probably occurred in the locations where closely related SIV strains were found Most SIV's infect monkey species whereas chimpanzees (like humans) are apes, it is observed that chimpanzees initially acquired SIV's from monkeys The opportunities for chimpanzee-or monkey-to-human host jumps have existed for hundreds or thousands of years and it is expected that such transmissions might have occurred in the past
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