Which of the following techniques would best be able to determine whether two cell types have differentiated from one another?

Below are I assume choices that should accompanied with question above.

a. Sequencing the DNA of the cell

b. Nucleic acid hybridization using DNA only

c. Nucleic acid hybridization using mRNA

d. Nuclear transfer

e. Gene silencing using RNAi

The should be e. Gene silencing using RNAi.