Some antibiotics administered to humans inhibit peptide formation in microbes. how were the antibiotics made to target the microbes and not the eukaryotic host?

The antibiotics target peptides that are not synthesized by the eukaryotic host but are synthesized by the microbes. Example is the targeting of peptides, and their precursors, like lipoteichoic acids, that are significant component of the peptidoglacan cell wall of Gram-positive bacteria.