At the time of fertilization in humans, two gametes, each containing a unique combination of alleles, fuse to form a diploid offspring. if you ignore crossing over, a single person can produce gametes with roughly how many different chromosome combinations

A human has 23 chromosome pairs (hence a total of 46 chromosomes). A gamete is haploid (n), hence has 23 total chromosomes. The number of combination of chromosomes that can make a gamete is calculated as follows; 2^23 = 8, 388, 608. This is without considering genetic recombination.