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17 June, 08:47

Based on the information in the passage, pdk1 catalyzes the addition of phosphate to what functional group

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  1. 17 June, 11:31
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    PDK1 (pyruvate dehydrogenase kinase 1) is an enzyme which inactivates the pyruvate dehydrogenase by phosphorylating it using an ATP molecule.

    PDK1 (phosphoinositide-dependent protein kinase-1) acts by catalyzing the phosphorylation of Thr-229 (threonine at position 229 in pyruvate dehydrogenase).

    This phosphorylation is synergistic with the phosphorylation of C-terminal Thr-389, but this one is not done by the PDK1.
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