Studies that fail to establish significant benefits of an intervention like medication are often never submitted for publication and instead filed away. the problem with this approach is that

The issue with this approach is that this inclination toward distributing just positive outcomes seriously constrains our capacity to assess the viability of antidepressants since we are just observing a cut of the real information. Further, a few scientists have addressed whether individuals with not as much as serious melancholy may have encountered positive outcomes in light of their desire of advantage, also called the misleading impact.