A nurse swabs your skin with rubbing alcohol, and you feel a cold spot created at that spot. what explains this cooling effect?

The cooling effect meaning that your skin releases alcohol molecules with the appropriate heat for it to evaporate. The alcohol is cold on your skin for the reason that when it comes in contact, the temperature of the body makes it change from fluid to gas, which pulls warm from the encompassing condition, including the skin. The aftereffect of this response is a chilly feeling.