What trend do you observe that distinguishes lone pairs from bonding domains?

Answer : The major distinguishing trend between the lone pairs and bodning domains is that a bonding pair has 2 electrons usually coming from different atoms, which overlaps to form a pi or sigma bond.

Whereas a lone pair or a a non-bonding pair is a pair of valence electrons that are not shared with another atom and is sometimes called a non-bonding pair.

In a nutshell, bonding pairs always take part in bonding whereas lone pairs never take part in bonding.

Lone pair is a pair of valence electrons that are not shared with another atom. The pair is also called a non-bonding pair.

The thing that distinguishes lone pairs from bonding domains is the following: The bonding domains are bonded to the central atom while the lone pairs are just stuck on as extra electrons.