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14 January, 05:13

What can be the problems encountered while using magnesium stearate as a lubricant with poorly soluble drug in hard gelatin capsules?

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Answers (1)
  1. 14 January, 07:36
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    The answer is explained below:

    Explanation:

    Magnesium stearate is primarily used as a lubricant and as anti-adherent and glidant. This occurs as plate-like crystals staked like a deck of cards.

    The use of magnesium stearate causes compression and dissolution problems.

    And because stearates are alkaline in reaction, it can not be used with some acidic drugs.
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