What range of PaO2 should be maintained in infants to minimize the risk of retinopathy of prematurity (ROP) ?

Answer: 50 to 80mmHg

Explanation:

Retinopathy of prematurity (ROP) is described as an ocular condition associated with O2 administration to premature infants. Excessive blood O2 levels produce retinal vasoconstriction, which (if prolonged) can result in permanent blindness. This risk poses a serious management problem, for the premature infant is often in need of supplemental O2. The American Academy of Pediatrics has recommended that keeping PaO2s between 50 to 80mmHg is the best way to minimize the risk of Retinopathy of Prematurity.