Cyanide is very toxic in high enough doses because it binds irreversibly to cytochrome C. Which of the following is not an effect of cyanide's inhibition of cytochrome C? Increase in the rate of the citric acid cycle's activity Increased ratio of ADP:ATP Build-up of NADH Increased pH in the mitochondrial intermembrane space

Question

Chemistry

Kenneth Patterson

30 June, 02:03

Cyanide is very toxic in high enough doses because it binds irreversibly to cytochrome C. Which of the following is not an effect of cyanide's inhibition of cytochrome C? Increase in the rate of the citric acid cycle's activity Increased ratio of ADP:ATP Build-up of NADH Increased pH in the mitochondrial intermembrane space

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Answers (1)

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Maximo Hatfield · Answer 1

a. The options are;

b. Increase in the rate of the citric acid cycle's activity

c. Increased ratio of ADP:ATP

d. Build-up of NADH

e. Increased pH in the mitochondrial intermembrane space

The correct option is;

b. Increase in the rate of the citric acid cycle's activity

Explanation:

The effects of cyanide's inhibition of chromosome C includes

1. It poisons the mitochondrial transport chain in cells resulting in the build up of NADH and makes the cells unable to produce energy from absorbed oxygen.

2. Due to the low level of ATP presence in the cell, there will be an increase in the rate of citric acid cycle

Thus, the rate of the cycle is reduced when the cell has a high level of ATP.

2. The introduction of cyanide rapidly decreases the level of ATP in the cell increasing the ratio of ADP to ATP

3. In the event of cyanide poisoning, the due to the interference of the electron transport to inter-membrane regions, the pH of the region will increase alongside a decrease in the pH gradient while the ATP formation would stop.