A virulence study was performed using Staphylococcus aureus in mice. It was determined that the LD50 for the S. aureus alpha-toxin was 0.045 µg/kg of body weight toxin (a relatively low LD50). In the same mouse population, the ID50 was determined to be 200,000 cells (a relatively high ID50). What do these results taken together mean?

Question

Chemistry

Kristen Kim

29 September, 14:44

A virulence study was performed using Staphylococcus aureus in mice. It was determined that the LD50 for the S. aureus alpha-toxin was 0.045 µg/kg of body weight toxin (a relatively low LD50). In the same mouse population, the ID50 was determined to be 200,000 cells (a relatively high ID50). What do these results taken together mean?

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Robert Mercer · Answer 1

S. aureus strain is less infectious, but its alpha-toxin is highly-toxic.

Explanation:

Given dа ta:

LD50 for S. aureus alpha toxin 0.45 / mu g/kg

ID50 for same mouse density found to be 200,000

From the data information given above Staphylococcus aureus was done on mice. The result show that LD50 is found to be 0.45/mu g/kg and ID50 found to be 200,000 on same mouse population

the result taken together mean that S. aureus strain is less infectious, but its alpha-toxin is highly-toxic.