What sequence of enzymes allows for the synthesis of glycogen from glucose-6-phosphate?

a. UDP-glucose pyrophosphorylase, phosphoglucomutase, glycogen synthase, amylo - (1,4α1,6) - transglycosylase

b. phosphoglucomutase, UDP-glucose pyrophosphorylase, amylo - (1,4α1,6) - transglycosylase, glycogen phosphorylase

c. phosphoglucomutase, amylo - (1,4α1,6) - transglycosylase, UDP-glucose pyrophosphorylase, glycogen synthase

d. UDP-glucose pyrophosphorylase, phosphoglucomutase, amylo - (1,4α1,6) - transglycosylase, glycogen synthase

e. phosphoglucomutase, UDP-glucose pyrophosphorylase, glycogen synthase, amylo - (1,4α1,6) - transglycosylase

Question

Chemistry

Slick

1 September, 19:11

What sequence of enzymes allows for the synthesis of glycogen from glucose-6-phosphate?

a. UDP-glucose pyrophosphorylase, phosphoglucomutase, glycogen synthase, amylo - (1,4α1,6) - transglycosylase

b. phosphoglucomutase, UDP-glucose pyrophosphorylase, amylo - (1,4α1,6) - transglycosylase, glycogen phosphorylase

c. phosphoglucomutase, amylo - (1,4α1,6) - transglycosylase, UDP-glucose pyrophosphorylase, glycogen synthase

d. UDP-glucose pyrophosphorylase, phosphoglucomutase, amylo - (1,4α1,6) - transglycosylase, glycogen synthase

e. phosphoglucomutase, UDP-glucose pyrophosphorylase, glycogen synthase, amylo - (1,4α1,6) - transglycosylase

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Answers (1)

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Delgado · Answer 1

The answer is (e) : phosphoglucomutase, UDP-glucose pyrophosphorylase, glycogen synthase then amylo - (1,4-1,6) - transglycosylase.

Explanation:

Phosphoglucomutase: Convert glucose-6-phosphate to glucose-1-phosphate.

UDP-glucose pyrophosphorylase: Form UDP-glucose from glucose-1-phosphate.

Glycogen synthase: Add the new glucose from UDP-glucose to the growing glycogen chain.

Amylo - (1,4-1,6) - transglycosylase: This is a branching enzyme, it initiates formation of branches evolving from the main chain.