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6 May, 14:29

In filling a hospital order, a pharmacist diluted 1 ml of an amphotericin b injection containing 50 mg/10 ml with a 5% w/v dextrose injection to prepare an intravenous infusion containing amphotericin b, 0.1 mg/ml. how many milliliters of infusion did the pharmacist prepare

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  1. 6 May, 18:05
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    Given:

    Initial volume of amphotericin V1 = 1 ml

    Initial concentration of amphotericin C1 = 50 mg/10 ml or 5 mg/ml

    Final concentration of amphotericin C2 = 0.1mg/ml

    To determine:

    The final volume V2 of the infusion containing amphotericin

    Explanation:

    Use the relation

    V1C1 = V2C2

    V2 = V1C1/C2 = 1 ml * 5 mg. ml-1/0.1 mg ml-1 = 50 ml

    Ans: The pharmacist prepared 50 ml of the infusion
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