You suspect that a serious developmental disorder is due to a chromosome abnormality and prepare a karyotype from an affected individual. in analyzing the karyotype, how could you distinguish trisomy from a chromosome structural defect such as a duplication?

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Chemistry

Branson Allison

25 September, 06:22

You suspect that a serious developmental disorder is due to a chromosome abnormality and prepare a karyotype from an affected individual. in analyzing the karyotype, how could you distinguish trisomy from a chromosome structural defect such as a duplication?

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Nicholas Mcmahon · Answer 1

The difference is very easy. In trisomy there would always be one extra chromosome. On the other hand, in a duplication one chromosome would have two copies of a portion of the chromosome.