Which of the four control methods is best suited for transfer of large blocks of data?

Answer: DMA (Direct Memory Access)

Explanation: DMA (Direct Memory Access) is the method out the four methods of large data transfer that are Channel I/O, Programmed I/O, Interrupt-driven I/O that is the most suitable for transferring of heavy amount of data

DMA has a major functioning device for the controlling the transfer process known as the DMA controller. This allow the input and output function of the data corresponding to the main memory.