Which of these playwrights is considered one of the greatest Greek writers of comic drama? Plautus Terence Seneca Aristophanes

This is of course somewhat subjective, but almost all classical historians agree that it was Aristophanes who was the most talented and influential comic writer of the age.

The correct answer is Aristophanes.

The most important reason why this is the correct answer is that the remaining three playwrights (Plautus, Terence, and Seneca) weren't Greek - all of them were Roman. Only Aristophanes was a Greek writer, so he is the correct answer. Additionally, Seneca is known for his tragedies, not comedies, whereas Terence and Plautus did write comedies, but they are not Greek.