What was the European impact on American Indians?

basically, European diseases wiped out almost all native Americans even before we made actual contact with most of them, and after that we just kept on conquering the remaining tribes.

The most common answer would be, they killed a lot of them. But I'll be a little specific:

- They brought unknown diseases to their bodies, killing them.

- They Claim almost all of their land, pushing them into Mexico.

- A good handful were put into slavery.