What was one of the major causes of death along the Trail of Tears for the Cherokee people?

A. Predators

B. Illness

C. Poison

D. Shootings

I'm thinking the answer would be B. Illness. The Native Americans who were forced through the Trail of Tears had to walk roughly a thousand miles with only the clothes on their backs. The death toll rose to nearly 4,000, of the original 16,000 who were forcibly relocated

B). Illness was one of the major causes. You have to remember that the Cherokee People, didn't have any doctors. Not to mention it was raining and in the middle of winter, so many people died. Either from the common cold, to hypothermia.