How do modern notions of the immense size and age of the universe affect your understanding of human history

"Our reach exceeds out grasp" Minute in the grand scheme of things.

Currently, we know that the age of universe is about 13.82 billion years old and the age of human history could only go as far as 200 thousand years ago. So, it is safe to assume that we will never know the origin of the universe because it already exist billion years away from our first appearance