In 1979, the National Commission for the protection of Humans Subjects of Biomedical and Behavioral Research developed ethical principles and guidelines for the protection of human subjects for research. The purpose of these guidelines was to:

Provide a framework for use in the resolution of ethical problem arising from research involving human subjects.

Explanation:

Framework issued by the National commission for the protection of Human subjects was known as Belmont report, its title was Ethical Principles and Guidelines for the protection of Human Subjects of Research.

The three core ethical principles and guidelines were to have respect for persons, Justice and Beneficence. It was issued on 30 September 1978 and was named after the Belmont Conference centre where the document was drafted.

In the report Respect for persons means to protect the autonomy of the people and treating them with respect, Beneficence refers to the philosophy of " Do not harm".

It means to minimise the risks to the research subjects while maximising the benefits for the research. While Justice means that the research procedures must be administered fairly. It must be reasonable and non exploitative and well considered