Which of these was the main cause of the spread of Hellenistic culture throughout the middle east and Asia?

A) the rise of the Roman Republic

B) the expansion of the Roman Empire

C) the success of the Persian Empire

D) the conquest of Alexander the Great

D) The conquest of Alexander the Great

The correct answer is D) the conquest of Alexander the Great

The main cause of the spread of Hellenistic culture throughout the middle east and Asia was "the conquest of Alexander the Great."

During the Hellenistic Age, the Greek culture, customs, and traditions expanded all over the territories conquered by the Greeks. It started in 323 BC with the death of Alexander the Great and ended with the conquest of the Macedonian territories by the Romans in 31 BC. After Alexander's death, his generals divided is conquest territories into three zones: the Ptolemies in Egypt, the Seleucids in Persia, and the Antoginids in Macedonia.