Thomas Jefferson welcomed the Missouri Compromise as a strong and permanent process to maintain the union.

True

False

False.

Explanation:

Missouri Compromise brought forth by John Holmes makes Missouri a slave trade and Maine as a free state. It also prohibited slavery north of the 36º 30' parallel.

Thomas Jefferson and his popular republican party were against this compromise for it threatens the balance of free and slave states. Jefferson expressed his disagreement of the Compromise in his letter to John Holmes, referring to the new Congress law as "the knell of the union [ ... ] hushed for the moment. But this is a reprieve only, not a final sentence." And he wholly disagrees with the division of the American union.

Thus, the correct answer is false for Jefferson did not welcome the Compromise but rather felt it further divided the union.