The Middle East is best known with which internationally traded product

Oil

Explanation:

The Middle East region is most famously known for its oil, which is traded internationally.

The Middle East is a region that goes from Egypt (West) to Iran (East) and from Turkey (North) to Yemen (South).

That region hold a large part of the world's reserves of oil and is mostly controlled by Royal families in non-democratic systems.

The oil made those countries extremely rich, since the other countries are buying this oil at a good price.