In what ways did gladiatorial combat change between the time of Julius Caesar in 46 B. C. and Constantine the Great in A. D. 312?

In the time of Julius Caesar, gladiatorial games were held on a regular basis for both celebration and hedonism. As time passed, the optics of the bloody gladiator combat games were less accepted. Constantine the Great made the spectacle illegal and closed all remaining constable stables and schools.