How do i simplify 2a x 3b x 4c

I don't think you can, because the letters are all different

In the expression 2a x 3b x 4c,

2, 3 and 4 are the coefficients and a, b and c are the variables.

When such a multiplications is given, multiply the coefficients together and the variables together.

So the product of coefficients = 2 * 3*4 = 24

the product of variables = a*b*c = abc

Finally multiply the product of coefficients and product of variables.

Final product = 24*abc = 24abc

So 24abc is the answer.