Pythagoras was born about 582 BC, Issac Newton was born in 1643 AD. how many years apart were they born?

B. C stands for before Christ, it means we count backward and A. D stands for Anno Domini, it means we count forward.

Pythagoras was born in 582 B. C

Newton was born in 1643 A. D

So, Total no. of years they born apart = 1643 + 582 = 2225 years apart