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30 July, 19:37

In examining a MRSA strain, researchers find that degraded penicillin is found in the culture medium. What is the most likely mechanism of resistance?

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  1. 30 July, 20:50
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    The production of beta-lactamase

    Explanation:

    Resistance is largely due to plasmid mediation with the most common mechanism being antibiotic hydrolysis. This is mediated by beta-lactamase (β-Lactamase) which converts penicillin to the inactive penicilloic. This conversion is enhanced by the acyl-enzyme intermediate, E-acyl.
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