In examining a MRSA strain, researchers find that degraded penicillin is found in the culture medium. What is the most likely mechanism of resistance?

The production of beta-lactamase

Explanation:

Resistance is largely due to plasmid mediation with the most common mechanism being antibiotic hydrolysis. This is mediated by beta-lactamase (β-Lactamase) which converts penicillin to the inactive penicilloic. This conversion is enhanced by the acyl-enzyme intermediate, E-acyl.