James suffers from atherosclerosis, w condition that causes artery walls to harden and thicken. Atherosclerosis restricts blood flow to organs and tissues. The restricted blood flow increases blood pressure in which system does atherosclerosis develop

Artherosclerosis develops in the nervous system.

Explanation:

Artherosclerosis is a condition that develops when plaque or fatty deposits block the arteries. This restricts the blood flow through the arteries partially or completely. Artherosclerosis can develop in the arteries of heart, brain or legs.

When the arteries are blocked by the thickening of the blood vessels the blood flow to the corresponding organs reduces. Thus the supply of oxygen and other vital nutrients to these parts reduces.

Based on the location of development of plaque and the type of artery affected various conditions arise.

Examples are coronary heart disease, angina, carotid artery disease, peripheral artery disease, chronic kidney disease etc.