The state in which a person's mental and physical abilities are impaired by alcohol or another substance is called a a blackout. b sobering up. c intoxication. d a hangover.

The answer is intoxication. Intoxication refers to the state wherein an individual’s mental and physical abilities are impaired or disabled by other substances, more likely by alcohol. Intoxication is commonly experienced by the use of alcohol, by getting drunk or drinking too much.