What personal tragedy prompted Harriet Beecher Stowe to write about the separation of black families under slavery?

The loss of her 18 month old son prompted Harriet Beecher Stowe tow rite for the slaves.

Explanation:

Harriet Beecher Stowe's Uncle tom Cabin is one of the most important pieces of writing for the slave rights that was influential in the 19th century US and is one of the bestselling books of its time.

The book was written by Harriet after she experienced a personal tragedy.

This was the death of her 18 month old son after which she focused her energy on inkling about the pain of slaves to work through her own personal pain and thus came about her novel.