Which pathway is generally followed by a protein produced for secretion? select one:

a. rough er, vesicle, golgi, vesicle

b. golgi, vesicle, smooth er, vesicle

c. smooth er, vesicle, golgi, vesicle

d. golgi, vesicle, rough er, vesicle?

The correct answer is "a" - rough er, vesicle, golgi, and then vesicle. This is due to the cells shearing the rough er into microsomes, passing into a vesicle, before moving through the golgi. These newly created secretions are then treated with proteases.