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1 June, 12:44

A group of scientists designed a clinical study to investigate the effects of cholesterol deficiency in humans. For the duration of the 8-week study, the adult subjects must live in a special research unit of a hospital. The only food the subjects can consume is a synthetic formula that contains all known nutrients, except cholesterol. Based on this information, you would expect:a. 100% of the subjects to show signs and symptoms of cholesterol deficiency within the first 3 weeks of participating in the study. b. about 50% of the subjects to show signs and symptoms of a cholesterol deficiency within the first week of the study. c. none of the subjects to show signs and symptoms of a cholesterol deficiency during the entire study. d. about 10% of the subjects to show signs and symptoms of a cholesterol deficiency within the first week of participating in the study.

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  1. 1 June, 14:50
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    c. none of the subjects to show signs and symptoms of a cholesterol deficiency during the entire study.

    Explanation:

    this is because the blood cholesterol is from two sources. Nearly 80% of the cholesterol the body needs are made by the liver and intestine. certain small amounts are also produced in the adrenal glands and the reproductive organs. The remaining fragment amounts comes from the diets.

    Therefore even if these subjects were fed with diet without cholesterol, it will not have any significant effects on the body cholesterol composition. Therefore no symptoms of its deficiency will be observed.

    Generally it biosynthesis is regulated by the amount of cholesterol present in the blood.
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