What is the most likely result if the shape of the enzyme changes?

If the shape of an enzyme changes then the enzyme will no longer be able to perform its function.

Enzymes can be described as bio-catalysts which usually speed up a chemical reaction. Each enzyme has a particular substrate which fits into the active site of the enzyme. Every enzyme needs a particular temperature and pH for its functioning. If the shape of an enzyme changes, then it will no longer be able to perform its function and will become denatured.