In bone formation, the cells that produce the organic matrix are the:

Osteoblasts

Osteoblasts are cells are responsible for the synthesis of bone formation. They are cuboidal cells that are located along the bone surface that comprises 4-6% of the total resident bone cells. Also, Osteoblast arise from mesenchymal stem cells (MSC) and MSC give rise to adipocytes, myocytes, Osteoblast and other cell types.