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8 January, 14:16

The lock and key model and the induced fit model are two models of enzyme action explaining both the specificity and the catalytic activity of enzymes. Indicate whether each statement is part of the lock and key model, the induced fit model, or is common to both models.

a. Enzyme conformation changes when it binds the substrate so the active site fits the substrate

b. Substrate binds to the enzyme at the active site, forming an enzyme-substrate complex

c. Enzyme active site has a rigid structure complementary

d. Substrate binds to the enzyme through noncovalent interactions

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  1. 8 January, 16:41
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    "The active site of the enzyme has a complementary rigid structure" belongs to the key and lock system

    "The conformation of the enzyme changes when it binds to the substrate so that the active site conforms to the substrate." belongs to the induced fit system.

    "The substrate binds to the enzyme at the active site, forming an enzyme-substrate complex" belongs to both, that is, the key and lock system and the induced fit system.

    "The substrate binds to the enzyme through non-covalent interactions" can belong to both enzyme systems.

    Explanation:

    Enzymatic key and lock systems bear this name because the enzyme at its site of union with the substrate has an ideal shape so that its fit is perfect, similar to a headbreaker, so once they are joined they are not It can bind another substrate to the enzyme, since they are generally associated with strong chemical bonds.

    The shape of the enzyme's active site is a negative of what the shape of the substrate would be.

    On the other hand, in the mechanism or enzyme system of induced adjustment, the enzyme has an active site that is where it binds with the substrate and another site where another chemical component binds, which when this chemical component binds this enzyme changes its morphology and becomes "active" to bond with your substrate.

    This happens a lot in the inactive enzymes that are usually activated in digestive processes since the fact that these enzymes are constantly active would be dangerous, therefore the body takes the induced enzyme system as a control mechanism, where a molecule or chemical compound induces change morphological of an enzyme by means of the allosteric union so that it joins its substrate and catalyzes or analyzes it, depending on the enzymatic character of the enzyme.
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