Chemistry

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16 July, 00:05

The Michaelis-Menten equation is an expression of the relationship between the initial velocity?0 of an enzymatic reaction and substrate concentration [S]. There are three conditions that are useful for simplifying the Michaelis-Menten equation to an expression from which the effect of [S] on the rate can be more readily determined. Match the condition (e. g., [S]=Km) with the statement or statements that describe it.

(1) Doubling [S] will almost double the rate.

(2) Half of the active sites are occupied by substrate.

(3) About 90% of the active sites are occupied by substrate.

(4) Doubling [S] will have little effect on the rate.

(5) Less than 10% of the active sites are occupied by substrate.

(6) This condition will result in the highest rate.